Doctors on the Front Lines Are Testing New Therapies to Treat COVID-19

Doctors on the Front Lines Are Testing New Therapies to Treat COVID-19

PR Newswire

PALM BEACH, Florida, June 3, 2020

- Financialnewsmedia.com News Commentary

PALM BEACH, Florida, June 3, 2020 /PRNewswire/ -- Researchers have been working furiously to identify medications to combat the novel coronavirus that causes COVID-19. While there are no definitive answers yet, the Food and Drug Administration (FDA) has authorized emergency use of the experimental drug remdesivir. That move came days after the early, unpublished results of a clinical trial showed that hospitalized patients who took the antiviral were discharged faster than those taking a placebo—in 11 days vs. 15. This emergency authorization will make remdesivir more widely available for the treatment of severe COVID-19, even as the agency noted there is still limited information about its safety and effectiveness. A recent article on the matter stated: "Although a 31 percent improvement doesn't seem like a knockout 100 percent, it is a very important proof of concept," Anthony Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), said on April 29, in a brief talk with the press. Investigators will soon look at whether remdesivir in combination with another medication may offer more robust effects, Fauci said. And researchers around the world are continuing to explore a number of other possible treatments."  Active biotech companies with recent developments include: Nascent Biotech, Inc. (OTCQB: NBIO), Moderna, Inc. (NASDAQ: MRNA), Vir Biotechnology, Inc. (NASDAQ: VIR), Pfizer Inc. (NYSE: PFE), Novavax, Inc. (NASDAQ: NVAX).

The article continued: "The Infectious Diseases Society of America (IDSA) recently released guidelines outlining which therapies are worth testing as potential treatments for this new disease that many doctors are still trying to understand. "We're learning a lot quickly—more so than we have with any other virus," says Paul Goepfert, M.D., professor of medicine and microbiology and director of the Alabama Vaccine Research Clinic at the University of Alabama at Birmingham… But it will take more rigorous studies before scientists truly know what will work best."

Nascent Biotech, Inc. (OTCQB: NBIO) BREAKING NEWS: Nascent Biotech's CEO Provides Corporate Updates on Phase I Brain Cancer Trial and COVID-19 Development Initiative on SNN Network
Nascent Biotech (the "Company" or "Nascent") is pleased to provide a corporate update and summary with a recent interview the Company's CEO, Sean Carrick, presented on SNN Network.  The complete interview may be seen on the SNN Network at https://www.youtube.com/watch?v=bq-iWU9Ss_E&t=93s. Mr. Carrick indicates, "As the Company moves forward with execution of its active 2020 agenda, key strategic initiatives will bring increased shareholder value to the Company. These include Nascent's landmark Phase 1 studies on its Pritumumab (PTB) antibody for brain cancer, COVID-19 in vitro studies, and the virus vaccine program."

During the interview Mr. Carrick updated the audience on a series of milestones completed by the Company including:

Read this entire press release and more news for NBIO at:   https://www.financialnewsmedia.com/news-nbio

Other industry developments from around the markets include:

Moderna, Inc. (NASDAQ: MRNA) a clinical stage biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines to create a new generation of transformative medicines for patients, recently announced that the first participants in each age cohort have been dosed in the Company's Phase 2 study of its mRNA vaccine candidate (mRNA-1273) against the novel coronavirus (SARS-CoV-2).

This Phase 2 study, being conducted by Moderna under its own Investigational New Drug (IND) application, will evaluate the safety, reactogenicity and immunogenicity of two vaccinations of mRNA-1273 given 28 days apart. The Company intends to enroll 600 healthy participants across two cohorts of adults ages 18-55 years (n=300) and older adults ages 55 years and above (n=300). Each participant will be assigned to receive placebo, a 50 μg or a 100 μg dose at both vaccinations. Participants will be followed through 12 months after the second vaccination. Given the 25 μg and 100 μg dose levels in the Phase 1 study showed neutralizing antibody titers at or above convalescent sera and were generally well tolerated, the Company has decided not to pursue the 250 μg dose level in the Phase 2 study.

Vir Biotechnology, Inc. (NASDAQ: VIR) recently announced that is has finalized a process development and manufacturing agreement with Biogen Inc. based on the letter of intent that the companies announced in March. Under the agreement Biogen will perform process development activities and specified manufacturing and process transfer services to enable commercial supply of Vir's SARS-CoV-2 monoclonal antibodies.

"Biogen's world-class cell line and process development expertise is a tremendous asset as we work with great urgency to develop our antibody candidates, including employing technology that is designed to maximize the yield of each manufacturing batch produced," said Michael Kamarck, Ph.D., Chief Technology Officer of Vir. "The willingness of both Vir and Biogen to begin work before the definitive agreement was in place exemplifies our shared commitment to working in unconventional ways in the interest of the public good, and mutual recognition that bringing these therapies to people at the speed and scale that is needed requires the combined resources of multiple collaboration partners and significant manufacturing capacity."

Pfizer Inc. (NYSE: PFE) recently announced the establishment of the Pfizer Breakthrough Growth Initiative, through which Pfizer will invest up to $500 million in biotechnology companies to help provide funding and access to Pfizer's scientific expertise to ensure continuity of the biotechnology companies' most promising clinical development programs.

"There has never been a more important moment to pursue new collaborations in our industry," said John Young, Pfizer's Chief Business Officer. "The Pfizer Breakthrough Growth Initiative seeks to do just this by injecting crucial capital into biotechnology companies that share our commitment to delivering transformative therapies for patients."

Novavax, Inc. (NASDAQ: NVAX) a late-stage biotechnology company developing next-generation vaccines for serious infectious diseases, recently announced the acquisition of Praha Vaccines a.s., part of the Cyrus Poonawalla Group, in an all cash transaction of approximately $167 million. The acquisition includes a biologics manufacturing facility and associated assets in Bohumil, Czech Republic. The facility is expected to provide an annual capacity of over 1 billion doses of antigen starting in 2021 for NVX–CoV2373, Novavax' COVID-19 vaccine candidate. NVX–CoV2373 consists of a stable, prefusion protein antigen made using its proprietary nanoparticle technology and includes Novavax' proprietary Matrix–M™ adjuvant.

"Manufacturing capacity is a critical component of our strategy to deliver a vaccine for the COVID-19 pandemic," said Stanley C. Erck, President and Chief Executive Officer of Novavax. "This acquisition provides the vital assets required to produce more than 1 billion doses per year. In parallel with ramping up production at Bohumil, we will continue efforts to expand antigen capacity in the U.S. and Asia, and increase production of Matrix-M to match antigen capacity at multiple sites globally."

DISCLAIMER:  FN Media Group LLC (FNM), which owns and operates Financialnewsmedia.com and MarketNewsUpdates.com, is a third- party publisher and news dissemination service provider, which disseminates electronic information through multiple online media channels. FNM is NOT affiliated in any manner with any company mentioned herein. FNM and its affiliated companies are a news dissemination solutions provider and are NOT a registered broker/dealer/analyst/adviser, holds no investment licenses and may NOT sell, offer to sell or offer to buy any security. FNM's market updates, news alerts and corporate profiles are NOT a solicitation or recommendation to buy, sell or hold securities. The material in this release is intended to be strictly informational and is NEVER to be construed or interpreted as research material.  All readers are strongly urged to perform research and due diligence on their own and consult a licensed financial professional before considering any level of investing in stocks. All material included herein is republished content and details which were previously disseminated by the companies mentioned in this release. FNM is not liable for any investment decisions by its readers or subscribers. Investors are cautioned that they may lose all or a portion of their investment when investing in stocks. For current services performed FNM was compensated twenty five hundred dollars for coverage of news issued by Nascent Biotech, Inc. by a non-affiliated third party. 

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